FARE GEBELİK DÖNEMİNDE HAREKETSİZLİK STRESİNİN PLASENTA VE YAVRUYA ETKİLERİ
نویسندگان
چکیده
ABSTRACT AIM: Stress can affect negatively mother and fetuses during pregnancy. We aimed to investigate the effects of chronic immobilization stress on placental maturation fetal development.MATERİALS AND METHODS: Balb/c virgin female mice (20-30 g) were mated with male in a 2 1 ratio. Pregnant control group (n=6) left undisturbed, whereas pregnant exposed 45 min for three times/day starting from gestational day 6 till 18. Fetuses placentas removed dams 18 under anesthesia.RESULTS: The prenatal significantly increased apoptosis several cells including trophoblastic giant cells, glycogen labyrinth resulted intrauterine growth restriction. caused decreased superoxide dismutase glutathione levels. Alizarin Red S staining shows ossification center see developmental abnormality. CONCLUSION: Gestational causes dysfunctions by triggering apoptosis, reducing zone as well increasing collagen levels, which may impair development that contribute pathogenesis
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ژورنال
عنوان ژورنال: Süleyman Demirel Üniversitesi T?p Fakültesi dergisi
سال: 2021
ISSN: ['1300-7416', '2602-2109']
DOI: https://doi.org/10.17343/sdutfd.651091